Friday, October 22

Science

See live cells with seven times greater sensitivity using new microscopy technique
Science

See live cells with seven times greater sensitivity using new microscopy technique

See live cells with seven times greater sensitivity using new microscopy techniqueExperts in optical physics have developed a new way to see inside living cells in greater detail using existing microscopy technology and without needing to add stains or fluorescent dyes. Since individual cells are almost translucent, microscope cameras must detect extremely subtle differences in the light passing through parts of the cell. Those differences are known as the phase of the light. Camera image sensors are limited by what amount of light phase difference they can detect, referred to as dynamic range. "To see greater detail using the same image sensor, we must expand the dynamic range so that we can detect smaller phase changes of light," said Associate Professor Takuro Ideguchi from the Universi...
Traditional Ghanaian medicines show promise against tropical diseases
Science

Traditional Ghanaian medicines show promise against tropical diseases

Traditional Ghanaian medicines show promise against tropical diseasesThe discovery of new drugs is vital to achieving the eradication of neglected tropical diseases (NTDs) in Africa and around the world. Now, researchers reporting in PLOS Neglected Tropical Diseases have identified traditional Ghanaian medicines which work in the lab against schistosomiasis, onchocerciasis and lymphatic filariasis, three diseases endemic to Ghana. The major intervention for NTDs in Ghana is currently mass drug administration of a few repeatedly recycled drugs, which can lead to reduced efficacy and the emergence of drug resistance. Chronic infections of schistosomiasis, onchocerciasis and lymphatic filariasis can be fatal. Schistosomiasis is caused by the blood flukes Schistosome haematobium and S. mansoni...
New research may explain severe virus attacks on the lungs
Science

New research may explain severe virus attacks on the lungs

New research may explain severe virus attacks on the lungsIn some cases, immune cells in the lungs can contribute to worsening a virus attack. In a new study, researchers at Karolinska Institutet in Sweden describe how different kinds of immune cells, called macrophages, develop in the lungs and which of them may be behind severe lung diseases. The study, which was published in Immunity, may contribute to future treatments for COVID-19, among other diseases. The structure of the lungs exposes them to viruses and bacteria from both the air and the blood. Macrophages are immune cells that, among other things, protect the lungs from such attacks. But under certain conditions, lung macrophages can also contribute to severe lung diseases, such as chronic obstructive pulmonary disease (COPD) and...
Scientists explore deficits in processing speed in individuals with spinal cord injury
Science

Scientists explore deficits in processing speed in individuals with spinal cord injury

Scientists explore deficits in processing speed in individuals with spinal cord injuryA team of rehabilitation researchers has studied processing speed deficits in individuals with spinal cord injury (SCI), comparing their brain activation patterns with those of healthy age-matched controls, and older healthy individuals. They found that the SCI group and older controls had similar activation patterns, but the SCI group differed significantly from their age-matched controls. The article, "The neural mechanisms underlying processing speed deficits in individuals who have sustained a spinal cord injury: A pilot study"  was published online on September 25, 2020 by Brain Topography. The authors are scientists with expertise in research in cognitive rehabilitation and SCI rehabilitation: ...